General information

Mutant name cin5-3 cul3hyp
Mutant/Transgenic plant mutant
Ecotype Col-0
Mutagenesis type cross of cul3hyp and cin5
Dominant/Recessive/Semi-dominant
PMID 19132085
CommentNo comment

Mutated genes

Locus name Alias Hormone Mutated site Paper description
AT5G65800 ACS5/ACC5/ETO2/CIN5 ethylene 1-aminocyclopropane-1-carboxylate synthase 5 (EC 4.4.1.14) (ACC synthase 5) (S-adenosyl-L-methionine methylthioadenosine-lyase 5) (Ethylene-overproduction protein 2);constitutive ethylene response;overproduce ethylene.AtACS5, a key enzyme of ethylene biosynthesis in etiolated seedling; loss-of-function mutation of AtACS5 (eto2-2) suppresses the phenotype of eto1
AT1G26830 CUL3A ethylene Cullin, putative, similar to Cullin homolog 3 (CUL-3) SP:Q13618, GI:3639052 from (Homo sapiens); contains Pfam profile PF00888: Cullin family. Interacts with other components of E3 ligase complex suggesting it functions in RUB-modification. Forms complexes with BTB domain proteins forming a novel class of E3-based ubiquitin protein-ligase complexes. Mutant is early flowering and has a reduced sensitivity to far-red light. cul3a/cul3b homozygous/heterozygous plants are embryo lethal.
AT1G69670 CUL3B ethylene T-DNA insertion in the first exon cullin, putative, contains similarity to Cullin homolog 3 (CUL-3) SP:Q13618, GI:3639052 from (Homo sapiens); contains Pfam profile PF00888: Cullin family. Interacts with members of AtBPM family and RBX1 suggesting it is part of an E3 ligase complex involved in RUB modification.

Phenotype information

Organ AttributeNo hormone
Root otherpartial suppress culhyp phenotype